Chicago based venture capital firms investing in early stage startups

ARCH is a venture firm specializing in life science innovations, aiming to prevent, detect, and cure diseases through investments across all stages, from seed to post-IPO. Established in 1986, they focus on high-impact scientific discoveries.

TechNexus fosters collaboration between leading corporations and ambitious entrepreneurs to create new business models, revenue streams, and markets. They primarily focus on early-stage investments, blending B2B and B2C strategies since 2007.

Pritzker Group Venture Capital partners with entrepreneurs to build market-leading technology companies. Since 1996, they have focused on early to late-stage ventures, offering deep industry expertise and strategic support.

Second Century Ventures promotes innovation within the real estate industry through strategic investments in early to late-stage ventures. Founded in 2009, they focus on technologies that enhance real estate, smart homes, and financial services.

Lightbank, a $700M AUM VC founded by serial entrepreneur Eric Lefkofsky, invests in SaaS, marketplaces, fintech, and consumer sectors. Since 2010, they have leveraged their expertise to support high-growth companies across multiple industries.

HPA is an early-stage investor providing venture capital and strategic support to companies in the financial services sector. Established in 2007, they focus on investments in fintech and related industries.

Hyde Park Venture Partners is an early-stage VC firm focusing on high-growth technology startups in the mid-continent U.S. market. Since 2011, they have invested in enterprise software, fintech, and financial services sectors.

IrishAngels is an angel investing network affiliated with the University of Notre Dame, investing in B2B, consumer, and medical companies. Established in 2012, they provide early-stage funding and strategic support to innovative startups.

OCA Ventures is an entrepreneur-friendly, hands-on early-stage VC firm. Founded in 1999, they focus on investments in the finance and venture capital sectors, offering collaborative support to early-stage companies.

M25 is the most active early-stage VC firm investing in Midwest-based startups across 14 states and over 100 companies. Since 2015, they have focused on a wide range of industries, offering tailored support to emerging enterprises.

Chicago Ventures leads seed rounds in finance, financial services, and venture capital. Since 2012, they have focused on early-stage investments, providing strategic guidance and capital to innovative startups.

Jump Capital is a thesis-driven, sector-focused VC firm specializing in Seed/Series A investments. Since 2012, they have provided operating-centric support to companies in fintech, SaaS, and digital media sectors.

S2G Ventures is a VC firm focused on food and agriculture industries, investing across all stages from seed to post-IPO. Founded in 2014, they support sustainable innovation in these critical sectors.

CMT Digital is a global blockchain and web3-focused trading and VC firm specializing in early-stage investments. Since 2017, they have concentrated on driving innovation in blockchain, cryptocurrency, and fintech.

TechRise Chicago is a multi-stakeholder initiative supporting Black and Latinx tech founders. Established in 2021, they provide early-stage funding, grants, and strategic support across diverse industries to foster innovation and inclusivity.

Cleveland Avenue is a VC firm investing in seed, early, and growth-stage companies across industries like AI, e-commerce, and food and beverage. Founded in 2015, they focus on scalable innovations in emerging sectors.

Origin Ventures is an early-stage VC firm investing in software and marketing companies that enable the Digital Native economy. Since 1999, they have supported startups in professional services and financial technology sectors.

Moderne Ventures invests in technology companies within real estate, finance, insurance, and sustainability sectors. Since 2015, they have focused on early to late-stage ventures, driving innovation across these critical industries.

G Squared is a growth-stage VC firm that invests privately in dynamic companies. Founded in 2011, they offer strategic support across various stages, from early to post-IPO, focusing on professional services and financial sectors.

Corazon Capital is a VC firm focused on early-stage opportunities in finance and venture capital. Since 2014, they have provided capital and strategic guidance to startups aiming to disrupt established markets.

First Analysis is a venture capital firm offering equity research, investment banking, and sales and trading services. Established in 1981, they focus on early to late-stage investments in the financial services and banking sectors.

Sandbox Industries bridges the gap between startups and corporations through strategic venture funds, accelerators, and consulting services. Founded in 2003, they invest in early to late-stage ventures across various industries.

Impact Engine is a VC and private equity firm investing in early-stage companies focused on education, health care, and sustainability. Since 2012, they have provided financial and human capital to drive impact-driven innovation.

MATH Venture Partners invests in teams with an unfair advantage in customer acquisition. Founded in 2014, they focus on early to late-stage ventures, providing strategic support to scalable businesses.

7wire Ventures invests in early and growth-stage companies focused on healthcare IT, digital healthcare, and mobile health. Since 2011, they have driven innovation in health and education sectors through strategic investments.

New Stack Ventures is a VC firm investing in pre-revenue startups in early commercialization phases. Founded in 2015, they focus on finance, internet, and venture capital sectors, providing early-stage capital and support.

Jumpstart Ventures is an investment fund partnering with entrepreneurs solving complex problems through intelligent innovation. Established in 2011, they focus on early to late-stage ventures in enterprise software and financial services.

Motivate Venture Capital is a venture firm investing in Pre-seed and Seed-stage companies across the US and Canada. Focused on Financial Services, Manufacturing, and SaaS, they specialize in early-stage ventures, supporting innovative startups since 2019.

Illinois Ventures is a seed and early-stage technology investment firm focused on research-derived companies in information technologies. Since 2000, they have been investing in innovative startups, particularly in Financial Services and Venture Capital, with a strong emphasis on early-stage ventures.

JK&B Capital is a VC firm focused on software, IT, and communications markets. Founded in 1996, they specialize in early and late-stage investments, leveraging deep industry knowledge to drive growth in tech companies.